Article
The quantity of nitric oxide released by macrophages regulates Chlamydia-induced disease.
Proceedings of the National Academy of Sciences of the United States of America - 19 Mar 2002
Huang Jin, DeGraves Fred J, Lenz Stephen D, Gao Dongya, Feng Pu, Li Dan, Schlapp Tobias, Kaltenboeck Bernhard
Abstract excerpt
Intracellular bacteria of the genus Chlamydia cause numerous typically chronic diseases, frequently with debilitating sequelae. Genetic determinants of disease susceptibility after infection with Chlamydia bacteria are unknown. C57BL/6 mice develop severe pneumonia and poor immunity against Chlamydia after moderate respiratory infection whereas BALB/c mice are protected from disease and develop vigorous Th1...
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