Article
Human Ro60 (SSA2) genomic organization and sequence alterations, examined in cutaneous lupus erythematosus.
The British journal of dermatology - 1 Feb 2002
Millard T P, Ashton G H S, Kondeatis E, Vaughan R W, Hughes G R V, Khamashta M A, Hawk J L M, McGregor J M, McGrath J A
Abstract excerpt
BACKGROUND: The Ro 60 kDa protein (Ro60 or SSA2) is the major component of the Ro ribonucleoprotein (Ro RNP) complex, to which an immune response is a specific feature of several autoimmune diseases. The genomic organization and any sequence variation within the DNA encoding Ro60 are unknown. OBJECTIVES: To characterize the Ro60 gene structure and to assess whether any sequence alterations might be associated...
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