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Ro60 and Y RNAs: structure, functions, and roles in autoimmunity

4 Mar 2019

Abstract excerpt

Ro60, also known as SS-A or TROVE2, is an evolutionarily conserved RNA-binding protein that is found in most animal cells, approximately 5% of sequenced prokaryotic genomes and some archaea. Ro60 is present in cells as both a free protein and as a component of a ribonucleoprotein complex, where its best-known partners are members of a class of noncoding RNAs called Y RNAs. Structural and biochemical analyses have...

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PMID: 31084369
DOI: 10.1080/10409238.2019.1608902

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