Article

Ro60 - Roles in RNA Processing, Inflammation, and Rheumatic Autoimmune Diseases

2024-06-13

Abstract excerpt

The Ro60 autoantigen is an RNA-binding protein, and a core component of nucleocytoplasmic ribonucleoprotein (RNP) complexes. Ro60 is essential in RNA metabolism, cell stress response pathways, and cellular homeostasis. It stabilises and mediates quality control and cellular dis-tribution of YRNAs, retroelement transcripts, and misfolded RNAs. Ro60 transcriptional dysregulation or loss of function can result in the...

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Literature Corpus work: e1063444-7e8d-5c91-9c1b-1544c39545f7
DOI: 10.20944/preprints202406.0929.v1

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