Article
Understanding biological dynamics: following cells and molecules to track functions and mechanisms.
European biophysics journal : EBJ - 1 May 2010
Palamidessi A, Testa I, Frittoli E, Barozzi S, Garrè M, Mazza D, Di Fiore P P, Diaspro A, Scita G, Faretta Mario
Abstract excerpt
The dissection of the molecular circuitries at the base of cell life and the identification of their abnormal transformation during carcinogenesis rely on the characterization of biological phenotypes generated by targeted overexpression or deletion of gene products through genetic manipulation. Fluorescence microscopy provides a wide variety of tools to monitor cell life with minimal perturbations. The...
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