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Article

Control of CpNpG DNA methylation by the KRYPTONITE histone H3 methyltransferase.

Nature - 4 Apr 2002

Jackson James P, Lindroth Anders M, Cao Xiaofeng, Jacobsen Steven E

Abstract excerpt

Gene silencing in eukaryotes is associated with the formation of heterochromatin, a complex of proteins and DNA that block transcription. Heterochromatin is characterized by the methylation of cytosine nucleotides of the DNA, the methylation of histone H3 at lysine 9 (H3 Lys 9), and the specific binding of heterochromatin protein 1 (HP1) to methylated H3 Lys 9 (refs 1-7). Although the relationship between these...

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Identifiers

PMID: 11898023
DOI: 10.1038/nature731

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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