Article
Dynamic evolution of the heterochromatin sensing histone demethylase IBM1.
PLoS genetics - 1 Jul 2024
Zhang Yinwen, Jang Hosung, Luo Ziliang, Dong Yinxin, Xu Yangyang, Kantamneni Yamini, Schmitz Robert J
Abstract excerpt
Heterochromatin is critical for maintaining genome stability, especially in flowering plants, where it relies on a feedback loop involving the H3K9 methyltransferase, KRYPTONITE (KYP), and the DNA methyltransferase CHROMOMETHYLASE3 (CMT3). The H3K9 demethylase INCREASED IN BONSAI METHYLATION 1 (IBM1) counteracts the detrimental consequences of KYP-CMT3 activity in transcribed genes. IBM1 expression in Arabidopsis...
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