Article
Genome-wide profiling of DNA methylation reveals transposon targets of CHROMOMETHYLASE3.
Current biology : CB - 8 Jan 2002
Tompa Rachel, McCallum Claire M, Delrow Jeffrey, Henikoff Jorja G, van Steensel Bas, Henikoff Steven
Abstract excerpt
DNA methylation has been implicated in a variety of epigenetic processes, and abnormal methylation patterns have been seen in tumors. Analysis of methylation patterns has traditionally been conducted either by using Southern analysis after cleavage with methyl-sensitive restriction endonucleases or by bisulfite sequencing. However, neither method is practical for analyzing more than a few genes. Here, we describe...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
