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Article

Truncated growth hormone receptor isoforms.

Acta paediatrica (Oslo, Norway : 1992). Supplement - 1 Feb 1999

Ross R J

Abstract excerpt

Truncated forms of the growth hormone receptor (GHR) that lack the majority of the cytoplasmic domain have been identified in a number of human tissues. In vitro, these truncated receptors act as dominant-negative inhibitors of the growth hormone (GH) signal and also generate large amounts of growth hormone binding protein (GHBP). Mutations that lead to high levels of expression of the truncated GHR are...

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Identifiers

PMID: 10102074
DOI: 10.1111/j.1651-2227.1999.tb14378.x

Genes

GHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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