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Article

The effect of the Interleukin-6-174G > C promoter gene polymorphism on endothelial function in healthy volunteers.

European journal of clinical investigation - 1 Mar 2002

Brull D J, Leeson C P M, Montgomery H E, Mullen M, deDivitiis M, Humphries S E, Deanfield J E, Lesson C P M

Abstract excerpt

AIMS: Atherosclerosis is a chronic inflammatory condition, manifest in its early stages by endothelial dysfunction. Interleukin-6 (IL6) plays a key role in driving this process through stimulation of acute phase protein synthesis. We have examined the effect of the IL6 gene -174G > C promoter polymorphism on endothelial function in a group of healthy subjects. METHODS: 248 adults aged 20-28 years participated....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 11895465
DOI: 10.1046/j.1365-2362.2002.00966.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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The effect of the Interleukin-6-174G > C promoter gene polymorphism on endothelial function in healthy volunteers.PMID 11895465Read ↗

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