Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phenotypic reversion in acute promyelocytic leukemia.

Nouvelle revue francaise d'hematologie - 1 Jan 1991

Degos L

Abstract excerpt

Acute promyelocytic leukemia (APL) is a clonal expansion of malignant cells blocked at a specific stage of myeloid differentiation. The disease is associated with a specific translocation between chromosome 17 and chromosome 15 t (15; 17) and with a bleeding diathesis previously attributed to a disseminated intravascular coagulation which is recently also related to a primary fibrinolysis. The high percentage of...

Topics

Carrier Proteins
Cell Differentiation
Gene Rearrangement
Humans
Leukemia, Promyelocytic, Acute
Neoplasm Proteins
Phenotype
Receptors, Retinoic Acid
Tretinoin

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 1667950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1667950-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phenotypic reversion in acute promyelocytic leukemia.PMID 1667950Read ↗

Variant and Masked Translocations in Acute Promyelocytic LeukemiaSemantic proximity Read ↗

NB4, a maturation inducible cell line with t(15;17) marker isolated from a human acute promyelocytic leukemia (M3)Semantic proximity Read ↗

Pathogenesis, Diagnosis and Monitoring of Residual Disease in Acute Promyelocytic LeukaemiaSemantic proximity Read ↗

Maturation sensitive and resistant t(15;17) NB4 cell lines as tools for APL physiopathology: nomenclature of cells and repertory of their known genetic alterations and phenotypes.Semantic proximity Read ↗

Retinoic acid and arsenic trioxide in the treatment of acute promyelocytic leukemia: current perspectivesSemantic proximity Read ↗

The unique aspects of acute promyelocytic leukemia.Semantic proximity Read ↗

Coagulopathy of Acute Promyelocytic LeukemiaSemantic proximity Read ↗

Clinical and molecular characterization of a rare syndrome of acute promyelocytic leukemia associated with translocation (11;17)Semantic proximity Read ↗

Utilization of molecular phenotypes to detect relapse and optimize the management of acute promyelocytic leukemia.Semantic proximity Read ↗

A retinoid acid 'resistant' t(15;17) acute promyelocytic leukemia cell line: isolation, morphological, immunological, and molecular features.Semantic proximity Read ↗

How retinoic acid and arsenic transformed acute promyelocytic leukemia therapySemantic proximity Read ↗

PATHOGENESIS AND TREATMENT OF THROMBOHEMORRHAGIC DIATHESIS IN ACUTE PROMYELOCYTIC LEUKEMIASemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.