Article
The effect of a novel intergenic polymorphism (rs11774572) on HDL-cholesterol concentrations depends on TaqIB polymorphism in the cholesterol ester transfer protein gene.
Nutrition, metabolism, and cardiovascular diseases : NMCD - 1 Jan 2010
Junyent M, Lee Y-C, Smith C E, Arnett D K, Tsai M Y, Kabagambe E K, Straka R J, Province M, An P, Lai C-Q, Parnell L D, Shen J, Borecki I, Ordovas J M
Abstract excerpt
BACKGROUND AND AIMS: Several genes have been shown to individually affect plasma lipoprotein metabolism in humans. Studies on gene-gene interactions could offer more insight into how genes affect lipid metabolism and may be useful in predicting lipid concentrations. We tested for gene-gene interactions between TaqIB SNP in the cholesterol ester transfer protein (CETP) and three novel single nucleotide...
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