Article
Activation of big mitogen-activated protein kinase-1 regulates smooth muscle cell replication.
Arteriosclerosis, thrombosis, and vascular biology - 1 Mar 2002
Luo Honglin, Reidy Michael A
Abstract excerpt
This study examined the activation of big mitogen-activated protein (MAP) kinase-1 (BMK1) in rat carotid smooth muscle cells (SMCs). Platelet-derived growth factor, fibroblast growth factor-2, sorbitol, and serum all increased the activation of BMK1 in rat carotid SMCs, whereas angiotensin II, phorbol esters, and tumor necrosis factor-alpha had only slight effects. With the exception of tumor necrosis...
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