Article
Adenoviral constructs encoding phosphorylation-competent full-length and truncated forms of the human retinoblastoma protein inhibit myocyte proliferation and neointima formation.
Circulation - 16 Sept 1997
Smith R C, Wills K N, Antelman D, Perlman H, Truong L N, Krasinski K, Walsh K
Abstract excerpt
BACKGROUND: The retinoblastoma (Rb) protein is a key cell-cycle regulator that controls entry into the S phase by modulating the activity of the E2F transcription factor. We analyzed the effects of full-length phosphorylation-competent and a mutant truncated form of human Rb for their effects on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.