Article
Conserved interactions with cytoskeletal but not signaling elements are an essential aspect of Drosophila WASp function.
Developmental biology - 15 Mar 2002
Tal Tamar, Vaizel-Ohayon Dalit, Schejter Eyal D
Abstract excerpt
Wiskott-Aldrich Syndrome proteins (WASp) serve as important regulators of cytoskeletal organization and function. These modular proteins, which are well-conserved among eukaryotic species, act to promote actin filament assembly in response to cues from various signal transduction pathways. Genetic analysis has revealed a requirement for the single Drosophila homolog, Wasp (Wsp), in cell-fate decisions governing...
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