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Article

Detection and mutation of a luxS-encoded autoinducer in Proteus mirabilis.

Microbiology (Reading, England) - 1 Mar 2002

Schneider Rachel, Lockatell C Virginia, Johnson David, Belas Robert

Abstract excerpt

Quorum sensing regulates the expression of virulence factors in a wide variety of pathogenic bacteria. This study has shown that Proteus mirabilis harbours a homologue of luxS, a gene required for the synthesis of the quorum sensing autoinducer 2 (AI-2). AI-2 activity is expressed during and is correlated with the initiation of swarming migration on agar surfaces. The P. mirabilis luxS locus was cloned and a...

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Identifiers

PMID: 11882712
DOI: 10.1099/00221287-148-3-773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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