Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

luxS mutants of Serratia defective in autoinducer-2-dependent 'quorum sensing' show strain-dependent impacts on virulence and production of carbapenem and prodigiosin.

Microbiology (Reading, England) - 1 Jun 2004

Coulthurst Sarah J, Kurz C Léopold, Salmond George P C

Abstract excerpt

The enzyme LuxS is responsible for the production of autoinducer-2 (AI-2), a molecule that has been implicated in quorum sensing in many bacterial species. This study investigated whether there is a luxS-dependent signalling system in the Gram-negative bacteria Serratia spp. Serratia marcescens is a broad-host-range pathogen and an important cause of nosocomial infections. Production of AI-2 activity was detected...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Caenorhabditis elegans
Share to Carbapenems

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Carbon-Sulfur Lyases

Share to Gene Expression Regulation, Bacterial

Share to Homoserine

Share to Lactones

Share to Serratia marcescens

Share to Virulence

Source

Identifiers

PMID: 15184576
DOI: 10.1099/mic.0.26946-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

luxS mutants of Serratia defective in autoinducer-2-dependent 'quorum sensing' show strain-dependent impacts on virulence and production of carbapenem and prodigiosin.PMID 15184576Read ↗

Isolation and functional analysis of luxS in Serratia plymuthica RVH1.Semantic proximity Read ↗

Quorum Sensing in ESKAPE Bugs: A Target for Combating Antimicrobial Resistance and Bacterial VirulenceSemantic proximity Read ↗

Mutation of luxS affects growth and virulence factor expression in Streptococcus pyogenes.Semantic proximity Read ↗

Quorum sensing in Clostridium difficile: analysis of a luxS-type signalling systemSemantic proximity Read ↗

<i>Enterococcus faecalis</i> V583 LuxS/AI-2 system is devoid of role in intra-species quorum-sensing but contributes to virulence in a <i>Drosophila</i> host modelSemantic proximity Read ↗

Detection and mutation of a luxS-encoded autoinducer in Proteus mirabilis.Semantic proximity Read ↗

Mechanisms of Inhibition of Quorum Sensing as an Alternative for the Control of E. coli and SalmonellaSemantic proximity Read ↗

AI-2-mediated signalling in bacteria.Semantic proximity Read ↗

AI-2 quorum sensing affects antibiotic susceptibility in Streptococcus anginosus.Semantic proximity Read ↗

Molecular Mechanism of Quorum-Sensing in Enterococcus faecalis: Its Role in Virulence and Therapeutic ApproachesSemantic proximity Read ↗

Investigation of LuxS-mediated quorum sensing in Klebsiella pneumoniae.Semantic proximity Read ↗

Distribution and Genetic Diversity of Genes Involved in Quorum Sensing and Prodigiosin Biosynthesis in the Complete Genome Sequences of Serratia marcescensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.