Article
Autoinducer-2-regulated genes in Streptococcus mutans UA159 and global metabolic effect of the luxS mutation.
Journal of bacteriology - 1 Jan 2008
Sztajer Helena, Lemme André, Vilchez Ramiro, Schulz Stefan, Geffers Robert, Yip Cindy Ying Yin, Levesque Celine M, Cvitkovitch Dennis G, Wagner-Döbler Irene
Abstract excerpt
Autoinducer 2 (AI-2) is the only species-nonspecific autoinducer known in bacteria and is produced by both gram-negative and gram-positive organisms. Consequently, it is proposed to function as a universal quorum-sensing signal for interaction between bacterial species. AI-2 is produced as the by-product of a metabolic transformation carried out by the LuxS enzyme. To separate the metabolic function of the LuxS...
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