Article
LuxS influences Escherichia coli biofilm formation through autoinducer-2-dependent and autoinducer-2-independent modalities.
FEMS microbiology ecology - 1 Mar 2013
Niu Chen, Robbins Chandan M, Pittman Kelly J, Osborn joDi L, Stubblefield Bryan A, Simmons Robert B, Gilbert Eric S
Abstract excerpt
Escherichia coli produces biofilms in response to the small molecule autoinducer-2 (AI-2), a product of the LuxS enzyme. LuxS is part of the activated methyl cycle and could also affect biofilm development by AI-2-independent effects on metabolism. A luxS deletion mutant of E. coli W3110 and an inducible plasmid-luxS-complemented strain were used to identify AI-2-independent phenotypes. Differential interference...
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