Article
Phenotype of apolipoprotein E influences the lipid metabolic response of postmenopausal women to hormone replacement therapy.
Maturitas - 30 May 2001
Tsuda M, Sanada M, Nakagawa H, Kodama I, Sakashita T, Ohama K
Abstract excerpt
OBJECTIVES: We investigated whether the phenotype of apolipoprotein E (apo E) would influence the response of postmenopausal Japanese women to hormone replacement therapy (HRT). METHODS: We measured the plasma levels of lipoprotein and apolipoprotein in 242 postmenopausal women at baseline and again after 12 months of HRT. Patients were divided into three groups according to apo E phenotype: E2+ (E2/2 and E2/3,...
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