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Article

Analysis of association between the Gln192Arg polymorphism of the paraoxonase gene and schizophrenia in humans.

Neuroscience letters - 22 Mar 2002

Matsumoto Chima, Ohmori Osamu, Hori Hiroko, Shinkai Takahiro, Nakamura Jun

Abstract excerpt

An increasing amount of evidence suggests a possible implication of oxidative stress in the pathophysiology of schizophrenia. Oxidized low-density lipoproteins (oxLDL) have been reported to be capable of eliciting neurocytotoxicity. On the other hand, paraoxonase (PON1), an arylesterase, plays a role in protection against oxidative modifications of LDL and is considered to be one of the antioxidant enzymes. Thus,...

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Source

Identifiers

PMID: 11880198
DOI: 10.1016/s0304-3940(02)00049-6

Genes

PON1

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Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of association between the Gln192Arg polymorphism of the paraoxonase gene and schizophrenia in humans.PMID 11880198Read ↗

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