Article
Mucin-like domain of enteropeptidase directs apical targeting in Madin-Darby canine kidney cells.
The Journal of biological chemistry - 1 Mar 2002
Zheng Xinglong, Sadler J Evan
Abstract excerpt
Enteropeptidase, a type II transmembrane protein of the enterocyte brush border, is sorted directly to the apical membrane of Madin-Darby canine kidney II cells. Apical targeting appears to be mediated by an N-terminal segment that contains a 27-amino acid residue O-glycosylated mucin-like domain consisting of two short mucin-like repeats, A and B. Targeting signals within these repeats were characterized by...
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