Article
Mammalian homolog of Drosophila tumor suppressor lethal (2) giant larvae interacts with basolateral exocytic machinery in Madin-Darby canine kidney cells.
Molecular biology of the cell - 1 Jan 2002
Müsch Anne, Cohen David, Yeaman Charles, Nelson W James, Rodriguez-Boulan Enrique, Brennwald Patrick J
Abstract excerpt
The Drosophila tumor suppressor protein lethal (2) giant larvae [l(2)gl] is involved in the establishment of epithelial cell polarity during development. Recently, a yeast homolog of the protein has been shown to interact with components of the post-Golgi exocytic machinery and to regulate a late step in protein secretion. Herein, we characterize a mammalian homolog of l(2)gl, called Mlgl, in the epithelial cell...
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