Article
[Separation and enrichment of fetal nucleated red blood cells from maternal blood for non-invasive prenatal gene diagnosis].
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi - 1 Oct 2000
Xie J, Long G
Abstract excerpt
OBJECTIVE: In order to develop a non-invasive technique for prenatal gene diagnosis. METHODS: Peripheral blood mononuclear cells (MNCs) were separated by single density gradient Histopaque 1.077 from 25 pregnant women with gestations between 8 - 36 weeks. The fetal nucleated red blood cells (NRBCs) were enriched from the MNCs by positive selection using Dynabeads M-450 CD(71) or negative selection using Dynabeads...
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