Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Noninvasive prenatal diagnosis of beta-thalassaemia using individual fetal erythroblasts isolated from maternal blood after enrichment.

Prenatal diagnosis - 1 Dec 2007

Kolialexi A, Vrettou C, Traeger-Synodinos J, Burgemeister R, Papantoniou N, Kanavakis E, Antsaklis A, Mavrou A

Abstract excerpt

Single nucleated red blood cells (NRBCs) isolated from maternal circulation were used for prenatal diagnosis of beta-thalassaemia. The study included 22 pregnant women in the first trimester, 6 carriers at risk for beta-thalassaemia and 16 noncarriers. Methodology involved enrichment of NRBCs by magnetic cell sorting (MACS) and microdissection of single NRBCs with a laser micromanipulation system. Single-cell...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to beta-Thalassemia
Share to Biomarkers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Fingerprinting

Share to Erythroblasts

Share to Globins

Share to Maternal-Fetal Exchange

Share to Pregnancy Trimester, First

Share to Prenatal Diagnosis

Source

Identifiers

PMID: 17987605
DOI: 10.1002/pd.1881

Genes

ADO
GABRB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Noninvasive prenatal diagnosis of beta-thalassaemia using individual fetal erythroblasts isolated from maternal blood after enrichment.PMID 17987605Read ↗

Enrichment of fetal cells from maternal blood by high gradient magnetic cell sorting (double MACS) for PCR-based genetic analysis.Semantic proximity Read ↗

Evaluation of beta-thalassemia in the fetus through cffDNA with multiple polymorphisms as a haplotype in the beta-globin gene.Semantic proximity Read ↗

Non-invasive prenatal paternity testing using cell-free fetal DNA from maternal plasma: DNA isolation and genetic marker studies.Semantic proximity Read ↗

Prenatal diagnosis from maternal blood: simultaneous immunophenotyping and FISH of fetal nucleated erythrocytes isolated by negative magnetic cell sorting.Semantic proximity Read ↗

Noninvasive prenatal diagnosis targeting fetal nucleated red blood cellsSemantic proximity Read ↗

[Separation and enrichment of fetal nucleated red blood cells from maternal blood for non-invasive prenatal gene diagnosis].Semantic proximity Read ↗

Identification of nucleated red blood cells in maternal circulation: A second step in screening for fetal aneuploidies and pregnancy complicationsSemantic proximity Read ↗

Aptamer-Mediated Enrichment of Rare Circulating Fetal Nucleated Red Blood Cells for Noninvasive Prenatal DiagnosisSemantic proximity Read ↗

Exploration of a Novel Noninvasive Prenatal Testing Approach for Monogenic Disorders Based on Fetal Nucleated Red Blood CellsSemantic proximity Read ↗

Clinical interpretation of cell-based non-invasive prenatal testing for monogenic disorders including repeat expansion disorders: potentials and pitfallsSemantic proximity Read ↗

Detection of paternally inherited fetal point mutations for β-thalassemia in maternal plasma using simple fetal DNA enrichment protocol with or without whole genome amplification: an accuracy assessment.Semantic proximity Read ↗

Embryo‐fetal erythroid cell selection from celomic fluid allows earlier prenatal diagnosis of hemoglobinopathiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.