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Noninvasive prenatal diagnosis targeting fetal nucleated red blood cells

30 Dec 2022

Abstract excerpt

Noninvasive prenatal diagnosis (NIPD) aims to detect fetal-related genetic disorders before birth by detecting markers in the peripheral blood of pregnant women, holding the potential in reducing the risk of fetal birth defects. Fetal-nucleated red blood cells (fNRBCs) can be used as biomarkers for NIPD, given their remarkable nature of carrying the entire genetic information of the fetus. Here, we review recent...

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PMID: 36585678
DOI: 10.1186/s12951-022-01749-3

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