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Article

Transfer of the Rf-1 region from FHH onto the ACI background increases susceptibility to renal impairment.

Physiological genomics - 28 Feb 2002

Provoost Abraham P, Shiozawa Masahide, Van Dokkum Richard P E, Jacob Howard J

Abstract excerpt

The genetically hypertensive fawn-hooded (FHH/Eur) rat is characterized by the early presence of systolic and glomerular hypertension, progressive proteinuria (UPV), and albuminuria (UAV), and focal glomerulosclerosis, resulting in premature death from renal failure. Previous studies showed that at least five genetic loci (Rf-1 to Rf-5) were linked to the development of renal impairment. Of these five, Rf-1...

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Source

Identifiers

PMID: 11875190
DOI: 10.1152/physiolgenomics.00030.2000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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