Article
Absence of an interaction between the Rf-1 and Rf-5 QTLs influencing susceptibility to renal damage in rats.
Nephron. Experimental nephrology - 1 Jan 2006
van Dijk Sabine J, Specht Patricia A C, Lazar Jozef, Jacob Howard J, Provoost Abraham P
Abstract excerpt
BACKGROUND: Previous studies showed that combining the Rf-1 and Rf-3 or Rf-4 QTLs of FHH induced synergistic interactions markedly enhancing renal susceptibility. The present study aimed to determine the presence of such interaction between the Rf-1 and Rf-5 QTLs. METHODS: Renal damage susceptibility was assessed in Rf-1B, Rf-1B+5, Rf-1B+4 congenics and ACI control rats in four situations: two-kidney control...
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