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Article

[Genetics analysis of microsatellite instability in patients from hereditary nonpolyposis colorectal cancer (HNPCC) families].

Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego - 1 Jul 2006

Smolarz Beata, Langner Ewa, Romanowicz-Makowska Hanna, Kozłowska Elzbieta, Kulig Andrzej, Dziki Adam

Abstract excerpt

UNLABELLED: Microsatellite instability (MSI) is due to defective DNA mismatch repair and is characteristic of HNPCC tumours. THE AIM: The role of MSI in familial predisposition to colorectal cancer was investigated in this study by microsatellite analysis among familial cases. MATERIAL AND METHODS: PCR-based microsatellite analysis was performed in blood obtained from 30 members from HNPCC families. Blood samples...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 17007286

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