Article

<em>P16</em> DNA Methylation Coupled with Somatic Copy Number Variations in the Development of Gastric Carcinomas

2026-04-15

Abstract excerpt

<h4>Background: </h4> /Objectives: Tumor suppressor genes are often inactivated by genetic and epigenetic mechanisms. However, whether genetic alterations of these genes, including CDKN2A/P16, are coupled with epigenetic changes in cancer development and progression is unknown. <h4>Methods:</h4> Freshly frozen gastric carcinoma (GC) samples, paired noncancer surgical margin (SM) samples, white blood cell (WBC) sam...

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Literature Corpus work: 1dde2147-1c2b-5503-8e04-301197848fa4
DOI: 10.20944/preprints202604.0988.v1

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