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Article

Computational studies of human prothrombin fragment 1, the Gla domain of factor IX and several biological interesting mutants.

Haemostasis - 1 Jan 1996

Li L, Darden T, Hiskey R, Pedersen L G

Abstract excerpt

We have employed molecular dynamics simulations to understand the properties of the gamma-carboxyglutamic acid (Gla) domains of human prothrombin fragment 1 (residues 1-144) and factor IX (residues 1-47). The simulations are based on (1) the crystal structure of bovine prothrombin fragment 1 in the presence of calcium and (2) our subsequent simulation of the solution structure for which we found accommodation of...

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PMID: 8904174
DOI: 10.1159/000217241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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