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Article

MALDI mass spectrometry analysis of single nucleotide polymorphisms by photocleavage and charge-tagging.

Nucleic acids research - 1 Jun 2003

Sauer Sascha, Lehrach Hans, Reinhardt Richard

Abstract excerpt

High-throughput procedures are an important requirement for future large-scale genetic studies such as genotyping of single nucleotide polymorphisms (SNPs). Matrix-assisted laser desorption/ ionisation mass spectrometry (MALDI-MS) has revolutionised the analysis of biomolecules and, in particular, provides a very attractive solution for the rapid typing of DNA. The analysis of DNA by MALDI can be significantly...

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Identifiers

PMID: 12771227
DOI: 10.1093/nar/gng062
PMCID: PMC156740

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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