Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Comparative electrostatic analysis of adenylyl cyclase for isoform dependent regulation properties.

Proteins - 1 Dec 2016

Tong Rudi, Wade Rebecca C, Bruce Neil J

Abstract excerpt

The enzyme adenylyl cyclase (AC) plays a pivotal role in a variety of signal transduction pathways inside the cell, where it catalyzes the cyclization of adenosine triphosphate (ATP) into the second-messenger cyclic adenosine monophosphate (cAMP). Among other roles, AC regulates processes involved in neural plasticity, innervation of smooth muscles of the heart and the endocrine system of the pancreas. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to GTP-Binding Protein alpha Subunits, Gi-Go
Share to GTP-Binding Protein beta Subunits

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Protein gamma Subunits

Share to Molecular Dynamics Simulation

Share to RGS Proteins

Share to Small Molecule Libraries

Share to Static Electricity

Source

Identifiers

PMID: 27667304
DOI: 10.1002/prot.25167

Genes

RGS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Comparative electrostatic analysis of adenylyl cyclase for isoform dependent regulation properties.PMID 27667304Read ↗

Isoform Specific Regulation of Adenylyl Cyclase 5 by GβγSemantic proximity Read ↗

The G-protein coupled receptor family: actors with many faces.Semantic proximity Read ↗

Two interaction sites on mammalian adenylyl cyclase type I and II: modulation by calmodulin and G(betagamma).Semantic proximity Read ↗

Guanylate cyclase-activating proteins: structure, function, and diversitySemantic proximity Read ↗

Isoforms of mammalian adenylyl cyclase: multiplicities of signaling.Semantic proximity Read ↗

The Family B1 GPCR: Structural Aspects and Interaction with Accessory ProteinsSemantic proximity Read ↗

Family-B G-protein-coupled receptors.Semantic proximity Read ↗

Mammalian adenylyl cyclase family members are randomly located on different chromosomes.Semantic proximity Read ↗

Adenylyl cyclase 9 as a molecular scaffold to dissect the regulatory mechanisms of membrane adenylyl cyclasesSemantic proximity Read ↗

The G protein database, GproteinDb.Semantic proximity Read ↗

Focus on molecules: guanylate cyclase-activating proteins (GCAPs).Semantic proximity Read ↗

Auto-inhibition of adenylyl cyclase 9 (AC9) by an isoform-specific motif in the carboxyl-terminal region.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.