Article
Intermolecular interactions between dimeric calcium-sensing receptor monomers are important for its normal function.
Proceedings of the National Academy of Sciences of the United States of America - 16 Mar 1999
Bai M, Trivedi S, Kifor O, Quinn S J, Brown E M
Abstract excerpt
We recently demonstrated that the G protein-coupled, extracellular calcium-sensing receptor (CaR) forms disulfide-linked dimers. The functional significance of dimerization of this receptor was suggested by our earlier observations that CaRs carrying certain point mutations exert dominant negativ...
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