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Article

Induction of dnaK through its native heat shock promoter is necessary for intramacrophagic replication of Brucella suis.

Infection and immunity - 1 Mar 2002

Köhler Stephan, Ekaza Euloge, Paquet Jean-Yves, Walravens Karl, Teyssier Jacques, Godfroid Jacques, Liautard Jean-Pierre

Abstract excerpt

The heat shock protein DnaK is essential for intramacrophagic replication of Brucella suis. The replacement of the stress-inducible, native dnaK promoter of B. suis by the promoter of the constitutively expressed bla gene resulted in temperature-independent synthesis of DnaK. In contrast to a dnaK null mutant, this strain grew at 37 degrees C, with a thermal cutoff at 39 degrees C. However, the constitutive dnaK...

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Identifiers

PMID: 11854256
DOI: 10.1128/IAI.70.3.1631-1634.2002
PMCID: PMC127800

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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