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Article

Dissection of the heat-shock response in Mycobacterium tuberculosis using mutants and microarrays.

Microbiology (Reading, England) - 1 Oct 2002

Stewart Graham R, Wernisch Lorenz, Stabler Richard, Mangan Joseph A, Hinds Jason, Laing Ken G, Young Douglas B, Butcher Philip D

Abstract excerpt

Regulation of the expression of heat-shock proteins plays an important role in the pathogenesis of Mycobacterium tuberculosis. The heat-shock response of bacteria involves genome-wide changes in gene expression. A combination of targeted mutagenesis and whole-genome expression profiling was used to characterize transcription factors responsible for control of genes encoding the major heat-shock proteins of M....

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PMID: 12368446
DOI: 10.1099/00221287-148-10-3129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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