Article
Role for dnaK locus in tolerance of multiple stresses in Staphylococcus aureus.
Microbiology (Reading, England) - 1 Sept 2007
Singh Vineet K, Utaida Sugunya, Jackson Letitia S, Jayaswal R K, Wilkinson Brian J, Chamberlain Neal R
Abstract excerpt
Heat-shock proteins are essential for stress tolerance and allowing organisms to survive conditions that cause protein unfolding. The role of the Staphylococcus aureus DnaK system in tolerance of various stresses was studied by disruption of dnaK by partial deletion and insertion of a kanamycin gene cassette. Deletion of dnaK in S. aureus strain COL resulted in poor growth at temperatures of 37 degrees C and...
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