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Article

Effect of heat shock and mutations in ClpL and ClpP on virulence gene expression in Streptococcus pneumoniae.

Infection and immunity - 1 Jul 2003

Kwon Hyog-Young, Kim Seung-Whan, Choi Moo-Hyun, Ogunniyi A David, Paton James C, Park Sin-Hee, Pyo Suhk-Neung, Rhee Dong-Kwon

Abstract excerpt

Spread of Streptococcus pneumoniae from the nasopharynx to other host tissues would require the organism to adapt to a variety of environmental conditions. Since heat shock proteins are induced by environmental stresses, we investigated the effect of heat shock on ClpL and ClpP synthesis and the effect of clpL and clpP mutations on the expression of key pneumococcal virulence genes. Pulse labeling with...

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Source

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Identifiers

PMID: 12819057
DOI: 10.1128/IAI.71.7.3757-3765.2003
PMCID: PMC162022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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