Article
Temporal Expression of the Candida albicans Genes CHK1 and CSSK1 , Adherence, and Morphogenesis in a Model of Reconstituted Human Esophageal Epithelial Candidiasis
1 Mar 2002
Abstract excerpt
We previously demonstrated that genes encoding a putative two-component histidine kinase (CHK1) or a response regulator (CSSK1) are each required for virulence in a murine model of hematogenously disseminated candidiasis and that strains with each gene deleted are also defective in morphogenesis under certain growth conditions. In the present study, the role of these two genes in the adherence to and colonization...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
