Comparative Transcript Profiling of Candida albicans and Candida dubliniensis Identifies <i>SFL2</i> , a C. albicans Gene Required for Virulence in a Reconstituted Epithelial Infection Model

Abstract excerpt

Candida albicans and Candida dubliniensis are closely related species displaying differences in virulence and genome content, therefore providing potential opportunities to identify novel C. albicans virulence genes. C. albicans gene arrays were used for comparative analysis of global gene expression in the two species in reconstituted human oral epithelium (RHE). C. albicans (SC5314) showed upregulation of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Antifungal resistance and susceptibility
• Share to Fungal Infections and Studies
• Share to Oral microbiology and periodontitis research