Article
Genetically regulated filamentation contributes to Candida albicans virulence during corneal infection.
Microbial pathogenesis - 1 Jan 2000
Jackson Beth E, Wilhelmus Kirk R, Mitchell Bradley M
Abstract excerpt
Candida albicans is a commensal fungus of the normal flora yet causes opportunistic infection following trauma or surgery and during immunosuppression. C. albicans virulence factors include morphogenesis into invasive filaments, adherence to host cells, and secretion of proteases. This study evaluated the role of fungal hyphal extension in experimental C. albicans keratitis using genetically altered yeast...
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