Article
A genomewide single-nucleotide-polymorphism panel for Mexican American admixture mapping.
American journal of human genetics - 1 Jun 2007
Tian Chao, Hinds David A, Shigeta Russell, Adler Sharon G, Lee Annette, Pahl Madeleine V, Silva Gabriel, Belmont John W, Hanson Robert L, Knowler William C, Gregersen Peter K, Ballinger Dennis G, Seldin Michael F
Abstract excerpt
For admixture mapping studies in Mexican Americans (MAM), we define a genomewide single-nucleotide-polymorphism (SNP) panel that can distinguish between chromosomal segments of Amerindian (AMI) or European (EUR) ancestry. These studies used genotypes for >400,000 SNPs, defined in EUR and both Pima and Mayan AMI, to define a set of ancestry-informative markers (AIMs). The use of two AMI populations was necessary...
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