Article
Admixture mapping as a tool in gene discovery.
Current opinion in genetics & development - 1 Jun 2007
Seldin Michael F
Abstract excerpt
Admixture mapping is a rapidly developing method to map susceptibility alleles in complex genetic disease associated with continental ancestry. Theoretically, when admixture between continental populations has occurred relatively recently, the chromosomal segments derived from the parental populations can be deduced from the differences in genotype allele frequencies. Progress in computational algorithms, in...
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