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Article

Association analysis for the genetic variants of the NMDA receptor subunit 2b and Alzheimer's disease.

Dementia and geriatric cognitive disorders - 1 Jan 2002

Tsai Shih-Jen, Liu Hsiu-Chih, Liu Tsung-Yun, Cheng Chih-Ya, Hong Chen-Jee

Abstract excerpt

N-methyl-D-aspartate (NMDA) receptor dysfunction has been implicated in the pathogenesis of Alzheimer's disease (AD). The NMDA receptor is composed of several subunits, of which the receptor 2b subunit (NR2b) is of particular significance for AD. Abundant in the hippocampus of normal subjects, reductions in NR2b have been demonstrated in the hippocampus and entorhinal cortex of AD patients. In this study, we...

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PMID: 11844890
DOI: 10.1159/000048639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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