Article
Further characterisation of transmissible spongiform encephalopathy phenotypes after inoculation of cattle with two temporally separated sources of sheep scrapie from Great Britain.
BMC research notes - 24 Jul 2015
Konold Timm, Nonno Romolo, Spiropoulos John, Chaplin Melanie J, Stack Michael J, Hawkins Steve A C, Cawthraw Saira, Wilesmith John W, Wells Gerald A H, Agrimi Umberto, Di Bari Michele A, Andréoletti Olivier, Espinosa Juan C, Aguilar-Calvo Patricia, Torres Juan M
Abstract excerpt
BACKGROUND: The infectious agent responsible for the bovine spongiform encephalopathy (BSE) epidemic in Great Britain is a transmissible spongiform encephalopathy (TSE) strain with uniform properties but the origin of this strain remains unknown. Based on the hypothesis that classical BSE may have been caused by a TSE strain present in sheep, cattle were inoculated intracerebrally with two different pools of...
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