Article
Emergence of Classical BSE Strain Properties during Serial Passages of H-BSE in Wild-Type Mice
14 Jan 2011
Abstract excerpt
BACKGROUND: Two distinct forms of atypical spongiform encephalopathies (H-BSE and L-BSE) have recently been identified in cattle. Transmission studies in several wild-type or transgenic mouse models showed that these forms were associated with two distinct major strains of infectious agents, which also differed from the unique strain that had been isolated from cases of classical BSE during the food-borne...
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