Article
Uncoupling protein 3 gene is associated with body composition changes with training in HERITAGE study.
Journal of applied physiology (Bethesda, Md. : 1985) - 1 Mar 2002
Lanouette Christian-Marc, Chagnon Yvon C, Rice Treva, Pérusse Louis, Muzzin Patrick, Giacobino Jean-Paul, Gagnon Jacques, Wilmore Jack H, Leon Arthur S, Skinner James S, Rao D C, Bouchard Claude
Abstract excerpt
The uncoupling protein 3 (UCP3) is a mitochondrial membrane transporter mainly expressed in skeletal muscle that we have shown to be associated with obesity. We have analyzed UCP3 polymorphisms, Val102Ile, Tyr210Tyr, and a new microsatellite GAIVS6 located in the sixth intron, among 276 black and 503 white subjects from the HERITAGE Family Study. Linkage and association studies were undertaken with body...
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