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Article

Association between two tumour necrosis factor intronic polymorphisms and HLA alleles.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Feb 2002

Low A S, Azmy I, Sharaf N, Cannings C, Wilson A G

Abstract excerpt

The gene for tumour necrosis factor (TNF) lies at the telomeric end of the class III region of the major histocompatibility complex (MHC). Polymorphisms within this gene have been implicated in the genetic background of a large number of common human diseases. Recently two polymorphisms, TNF +489 and +691, have been described in the first intron of TNF (+489, G to A transition; +691, G deletion) and disease...

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Source

Identifiers

PMID: 11841486
DOI: 10.1046/j.1365-2370.2002.00273.x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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