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Article

Genetic approaches to studying virulence and pathogenesis in Toxoplasma gondii.

Philosophical transactions of the Royal Society of London. Series B, Biological sciences - 29 Jan 2002

Sibley L David, Mordue Dana G, Su Chunlei, Robben Paul M, Howe Dan K

Abstract excerpt

Toxoplasma gondii is a common protozoan parasite that causes disease in immunocompromised humans. Equipped with a wide array of experimental tools, T. gondii has rapidly developed as a model parasite for genetic studies. The population structure of T. gondii is highly clonal, consisting of three distinct lineages that differ dramatically in virulence. Acute virulence is probably mediated by the genetic...

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Identifiers

PMID: 11839185
DOI: 10.1098/rstb.2001.1017
PMCID: PMC1692920

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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