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Genetic Mapping of Pathogenesis Determinants in Toxoplasma gondii

30 Jun 2016

Abstract excerpt

Toxoplasma gondii is a widespread parasite of warm-blooded vertebrates that also causes opportunistic infections in humans. Rodents are a natural host for asexually replicating forms, whereas cats serve as the definitive host for sexual development. The laboratory mouse provides a model to study pathogenesis. Strains of T. gondii are globally diverse, with more than 16 distinct haplogroups clustered into 6 major...

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PMID: 27359216
DOI: 10.1146/annurev-micro-091014-104353

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